After 45 years of hosting the Jerry Lewis Muscular Dystrophy Telethon, the 85 year old comedian is calling it quits saying it's  "time for an all new Telethon era.", according to a statement released through the association. Lewis will be making his final appearance on the telethon this fall.

"Lewis' first live Labor Day weekend telethon in 1966 was broadcast by a single New York City television station. It raised more than $1 million in pledges.

One of the most memorable moments on the telethon came in 1976 when Jerry was reunited live with Frank Sinatra and Dean Martin. The three had an acrimonious split 20 years earlier.

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